PT  - JOURNAL ARTICLE
AU  - George Aragon
AU  - Zobair M. Younossi
TI  - When and how to evaluate mildly elevated liver enzymes in apparently healthy patients
AID  - 10.3949/ccjm.77a.09064
DP  - 2010 Mar 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 195--204
VI  - 77
IP  - 3
4099  - http://www.ccjm.org/content/77/3/195.short
4100  - http://www.ccjm.org/content/77/3/195.full
SO  - Cleve Clin J Med2010 Mar 01; 77
AB  - Because 1% to 9% of people without symptoms have elevated liver enzymes, extensive evaluation of all abnormal test results would expose many patients to undue risks and expenses. On the other hand, failure to evaluate minor liver enzyme elevations could mean missing the early diagnosis of potentially treatable disorders. This review discusses likely causes of elevated aminotransferase, alkaline phosphatase, and gamma-glutamyl transferase levels and provides algorithms for evaluating high liver enzyme values in apparently healthy patients in the primary care setting.