RT Journal Article
SR Electronic
T1 When and how to evaluate mildly elevated liver enzymes in apparently healthy patients
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 195
OP 204
DO 10.3949/ccjm.77a.09064
VO 77
IS 3
A1 George Aragon
A1 Zobair M. Younossi
YR 2010
UL http://www.ccjm.org/content/77/3/195.abstract
AB Because 1% to 9% of people without symptoms have elevated liver enzymes, extensive evaluation of all abnormal test results would expose many patients to undue risks and expenses. On the other hand, failure to evaluate minor liver enzyme elevations could mean missing the early diagnosis of potentially treatable disorders. This review discusses likely causes of elevated aminotransferase, alkaline phosphatase, and gamma-glutamyl transferase levels and provides algorithms for evaluating high liver enzyme values in apparently healthy patients in the primary care setting.