RT Journal Article
SR Electronic
T1 New tools for detecting occult monoclonal gammopathy, a cause of secondary osteoporosis
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 273
OP 278
DO 10.3949/ccjm.77a.09091
VO 77
IS 4
A1 Faiman, Beth
A1 Licata, Angelo A.
YR 2010
UL http://www.ccjm.org/content/77/4/273.abstract
AB Most patients with multiple myeloma or other monoclonal gammopathies present with anemia, hypercalcemia, or renal insufficiency. However, osteoporosis may be the first sign. Measuring the concentration and ratio of free light chains in the serum can help detect monoclonal gammopathy and help to differentiate myeloma-related bone loss from other secondary forms of osteoporosis.