RT Journal Article SR Electronic T1 Noninvasive positive pressure ventilation: Increasing use in acute care JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 307 OP 316 DO 10.3949/ccjm.77a.09145 VO 77 IS 5 A1 Aboussouan, Loutfi S. A1 Ricaurte, Basma YR 2010 UL http://www.ccjm.org/content/77/5/307.abstract AB In the past 2 decades, noninvasive positive pressure ventilation (NIPPV) has been increasingly used in acute respiratory failure to avoid the risks associated with intubation. It is now considered standard first-line therapy in several situations. In this review, we summarize how NIPPV has evolved, the current level of evidence that supports its use in various clinical situations, its potential contraindications, and its limitations in acute respiratory failure.