PT - JOURNAL ARTICLE AU - Hanna, Elias B. AU - Hennebry, Thomas A. AU - Abu-Fadel, Mazen S. TI - Combined reperfusion strategies in ST-segment elevation MI: Rationale and current role AID - 10.3949/ccjm.77a.10024 DP - 2010 Sep 01 TA - Cleveland Clinic Journal of Medicine PG - 629--638 VI - 77 IP - 9 4099 - http://www.ccjm.org/content/77/9/629.short 4100 - http://www.ccjm.org/content/77/9/629.full SO - Cleve Clin J Med2010 Sep 01; 77 AB - Primary percutaneous coronary intervention (PCI) is the preferred reperfusion strategy for ST-elevation myocardial infarction (MI), but most patients do not arrive at a PCI facility within the recommended 90 minutes of first medical contact. If delay is expected, timely thrombolysis is recommended, followed by early transfer for PCI. The authors review the rationale behind three combined reperfusion strategies—facilitated PCI, pharmacoinvasive therapy, and rescue PCI—and data on their effectiveness.