RT Journal Article
SR Electronic
T1 Management of hyponatremia: Providing treatment and avoiding harm
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 715
OP 726
DO 10.3949/ccjm.77a.08051
VO 77
IS 10
A1 Vaidya, Chirag
A1 Ho, Warren
A1 Freda, Benjamin J.
YR 2010
UL http://www.ccjm.org/content/77/10/715.abstract
AB Hyponatremia, in its most severe form, requires urgent infusion of hypertonic saline to correct cerebral edema. However, overly rapid correction of chronic hyponatremia can cause osmotic demyelination syndrome. The authors review the treatment of hyponatremia in order to provide clinicians with a sound approach in a variety of settings in which severity, symptoms, and underlying disease states influence therapy. Also discussed is the current role of vasopressin antagonists in treatment.