RT Journal Article SR Electronic T1 The homocysteine hypothesis: Still relevant to the prevention and treatment of cardiovascular disease? JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 911 OP 918 DO 10.3949/ccjm.77a.10036 VO 77 IS 12 A1 Abraham, Joellyn M. A1 Cho, Leslie YR 2010 UL http://www.ccjm.org/content/77/12/911.abstract AB Although evidence suggests that the homocysteine hypothesis is still relevant as a predictor of cardiovascular risk, we cannot conclude that measuring the homocysteine level is useful in guiding treatment. Furthermore, studies of primary and secondary prevention show no evidence that taking folic acid or other B vitamins lowers the risk of cardiovascular events.