TY - JOUR T1 - The homocysteine hypothesis: Still relevant to the prevention and treatment of cardiovascular disease? JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 911 LP - 918 DO - 10.3949/ccjm.77a.10036 VL - 77 IS - 12 AU - Joellyn M. Abraham AU - Leslie Cho Y1 - 2010/12/01 UR - http://www.ccjm.org/content/77/12/911.abstract N2 - Although evidence suggests that the homocysteine hypothesis is still relevant as a predictor of cardiovascular risk, we cannot conclude that measuring the homocysteine level is useful in guiding treatment. Furthermore, studies of primary and secondary prevention show no evidence that taking folic acid or other B vitamins lowers the risk of cardiovascular events. ER -