PT  - JOURNAL ARTICLE
AU  - Mike J.L. Dejongste
AU  - Gert J. Terhorst
AU  - Robert D. Foreman
TI  - Basic research models for the study of underlying mechanisms of electrical neuromodulation and ischemic heart-brain interactions
AID  - 10.3949/ccjm.76.s2.09
DP  - 2009 Feb 01
TA  - Cleveland Clinic Journal of Medicine
PG  - S41--S46
VI  - 76
IP  - 4 suppl 2
4099  - http://www.ccjm.org/content/76/4_suppl_2/S41.short
4100  - http://www.ccjm.org/content/76/4_suppl_2/S41.full
SO  - Cleve Clin J Med2009 Feb 01; 76
AB  - The study of mechanisms of action underlying the use of electrical neuromodulation for angina and myocardial ischemia may illuminate heart-brain interactions that influence these conditions. To investigate these mechanisms of action, we initiated a neurocardiology program in the 1990s. This review discusses the experimental models we have studied to unravel the heart-brain interactions involved in the use of electrical neuromodulation for ischemic disease.