TY - JOUR T1 - Basic research models for the study of underlying mechanisms of electrical neuromodulation and ischemic heart-brain interactions JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - S41 LP - S46 DO - 10.3949/ccjm.76.s2.09 VL - 76 IS - 4 suppl 2 AU - Mike J.L. Dejongste AU - Gert J. Terhorst AU - Robert D. Foreman Y1 - 2009/02/01 UR - http://www.ccjm.org/content/76/4_suppl_2/S41.abstract N2 - The study of mechanisms of action underlying the use of electrical neuromodulation for angina and myocardial ischemia may illuminate heart-brain interactions that influence these conditions. To investigate these mechanisms of action, we initiated a neurocardiology program in the 1990s. This review discusses the experimental models we have studied to unravel the heart-brain interactions involved in the use of electrical neuromodulation for ischemic disease. ER -