RT Journal Article
SR Electronic
T1 Basic research models for the study of underlying mechanisms of electrical neuromodulation and ischemic heart-brain interactions
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP S41
OP S46
DO 10.3949/ccjm.76.s2.09
VO 76
IS 4 suppl 2
A1 Mike J.L. Dejongste
A1 Gert J. Terhorst
A1 Robert D. Foreman
YR 2009
UL http://www.ccjm.org/content/76/4_suppl_2/S41.abstract
AB The study of mechanisms of action underlying the use of electrical neuromodulation for angina and myocardial ischemia may illuminate heart-brain interactions that influence these conditions. To investigate these mechanisms of action, we initiated a neurocardiology program in the 1990s. This review discusses the experimental models we have studied to unravel the heart-brain interactions involved in the use of electrical neuromodulation for ischemic disease.