PT - JOURNAL ARTICLE AU - Michael G. (Monty) Mythen TI - Postoperative gastrointestinal tract dysfunction: An overview of causes and management strategies AID - 10.3949/ccjm.76.s4.11 DP - 2009 Nov 01 TA - Cleveland Clinic Journal of Medicine PG - S66--S71 VI - 76 IP - 10 suppl 4 4099 - http://www.ccjm.org/content/76/10_suppl_4/S66.short 4100 - http://www.ccjm.org/content/76/10_suppl_4/S66.full SO - Cleve Clin J Med2009 Nov 01; 76 AB - Postoperative gastrointestinal (GI) tract dysfunction is common and has a complex, multifactorial pathogenesis. Perioperative administration of targeted amounts of fluid to optimize ventricular filling and end-organ perfusion has consistently been shown to improve mortality and other outcomes, particularly GI tract perfusion and function. The choice of fluid loading affects postoperative recovery, with colloid showing superiority over crystalloid, and lactated Ringer’s solution proving better than normal saline. Other methods of reducing postoperative GI tract dysfunction with some proven degree of success include simple, low-cost interventions such as early initiation of oral feeding, early use of laxatives, and gum chewing. There is no evidence that prophylactic nasogastric decompression accelerates return of bowel function.