PT - JOURNAL ARTICLE AU - Bradley N. Gaynes AU - A. John Rush AU - Madhukar H. Trivedi AU - Stephen R. Wisniewski AU - Donald Spencer AU - Maurizio Fava TI - The STAR*D study: Treating depression in the real world DP - 2008 Jan 01 TA - Cleveland Clinic Journal of Medicine PG - 57--66 VI - 75 IP - 1 4099 - http://www.ccjm.org/content/75/1/57.short 4100 - http://www.ccjm.org/content/75/1/57.full SO - Cleve Clin J Med2008 Jan 01; 75 AB - The Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study evaluated feasible treatment strategies to improve clinical outcomes for real-world patients with treatment-resistant depression. Although the study found no clear-cut “winner,” it does provide guidance on how to start therapy and how to proceed if initial treatment fails.