RT Journal Article SR Electronic T1 Case study in heart-brain interplay: A 53-year-old woman recovering from mitral valve repair JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP S10 OP S14 VO 75 IS 3 suppl 2 A1 Callahan, Thomas D. A1 Khokhar, Ubaid A1 Pozuelo, Leo A1 Young, James B. YR 2008 UL http://www.ccjm.org/content/75/3_suppl_2/S10.abstract AB This article presents the case of a 53-year-old female attorney who underwent successful mitral valve repair for mitral valve prolapse. The patient’s postoperative course was marked by refractory pain, fatigue, shortness of breath, refusal to ambulate, frequent episodes of tearfulness, and a postsurgical decline in ejection fraction through postoperative week 4. Her slow recovery prompted a psychiatric consult, during which she reported panic and a fear of “losing it.” After respective presentations of the case from the cardiology and psychiatry perspectives, the article concludes with a moderated discussion of the case to explore insights it provides into heart-brain interactions.