PT - JOURNAL ARTICLE AU - David L. Longworth TI - Update on infectious disease prevention: Human papillomavirus, hepatitis A DP - 2008 Jun 01 TA - Cleveland Clinic Journal of Medicine PG - 402--410 VI - 75 IP - 6 4099 - http://www.ccjm.org/content/75/6/402.short 4100 - http://www.ccjm.org/content/75/6/402.full SO - Cleve Clin J Med2008 Jun 01; 75 AB - Key studies on the prevention of human papillomavirus and hepatitis A published during the past year found that: A quadrivalent vaccine against human papillomavirus prevents cervical intraepithelial neoplasia, vulvar and vaginal intraepithelial neoplasia, and anogenital disease in young women. The vaccine is likely cost-effective when given to girls, but perhaps not when given to boys.Although hepatitis A immune globulin is modestly better than hepatitis A vaccine for postexposure prophylaxis against hepatitis A, both are highly effective. Hepatitis A vaccine is now recommended by the Advisory Committee on Immunization Practices as the preferred agent in healthy individuals between the ages of 2 and 40.