RT Journal Article
SR Electronic
T1 Bisphosphonates and osteonecrosis of the jaw: Innocent association or significant risk?
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 871
OP 879
DO 10.3949/ccjm.75a.08014
VO 75
IS 12
A1 Carey, John J.
A1 Palomo, Leena
YR 2008
UL http://www.ccjm.org/content/75/12/871.abstract
AB Published case series and systematic reviews have documented an association between bisphosphonates and osteonecrosis of the jaw. However, a cause-and- effect relationship has not been established, and most of the reported cases have been in patients with cancer who were receiving much higher doses than those used to treat osteoporosis or Paget disease of bone. The risk, if any, to patients with these latter conditions receiving these drugs appears to be very small.