PT - JOURNAL ARTICLE AU - Chisolm, Guy M. AU - Kahn, Jeffrey P. TI - Beyond disclosure: The necessity of trust in biomedical research DP - 2007 Mar 01 TA - Cleveland Clinic Journal of Medicine PG - S49--S50 VI - 74 IP - 3 suppl 2 4099 - http://www.ccjm.org/content/74/3_suppl_2/S49.short 4100 - http://www.ccjm.org/content/74/3_suppl_2/S49.full SO - Cleve Clin J Med2007 Mar 01; 74 AB - Biomedical research is experiencing a crisis in public trust. Although the vast majority of clinical studies are conducted in an ethical fashion, public perceptions are fueled by well-publicized examples of unethical practices. Mistrust is further encouraged by the duality of the role of the clinical researcher, who is charged with both caring for patients and answering a research question. Disclosure is not adequate to fully address conflicts of interest in biomedical research; instead, efforts to protect patients’ interests and enhance trust should combine disclosure with an attempt to reduce conflicts in the first place as much as possible.