PT  - JOURNAL ARTICLE
AU  - Monique L. Giroux
TI  - Parkinson disease: Managing a complex, progressive disease at all stages
DP  - 2007 May 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 313--328
VI  - 74
IP  - 5
4099  - http://www.ccjm.org/content/74/5/313.short
4100  - http://www.ccjm.org/content/74/5/313.full
SO  - Cleve Clin J Med2007 May 01; 74
AB  - Parkinson disease is a complex neurodegenerative disease with both motor and nonmotor symptoms. Levodopa remains the mainstay of therapy but is associated with motor complications as the disease progresses. A levodopa-sparing strategy may reduce or delay the onset of motor complications. New medical and surgical therapies offer improved control of motor complications in advancing disease. Recognition and treatment of nonmotor symptoms can improve quality of life throughout the course of the disease.