PT - JOURNAL ARTICLE AU - O’Shea, Robert TI - Chronic hepatitis B virus infection: Issues in treatment DP - 2007 Aug 01 TA - Cleveland Clinic Journal of Medicine PG - 557--560 VI - 74 IP - 8 4099 - http://www.ccjm.org/content/74/8/557.short 4100 - http://www.ccjm.org/content/74/8/557.full SO - Cleve Clin J Med2007 Aug 01; 74 AB - As research continues to define the optimal management of chronic hepatitis B virus (HBV) infection, clinicians must deal with a number of yet unresolved issues: Should we treat all patients with HBV infection to prevent liver cancer, even if they have no evidence of active disease? Which is the best treatment strategy? What do we do with patients who develop resistance to our current drugs? Should we treat patients with HBV infection who have already developed cirrhosis?