RT Journal Article SR Electronic T1 Chronic hepatitis B virus infection: Issues in treatment JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 557 OP 560 VO 74 IS 8 A1 O’Shea, Robert YR 2007 UL http://www.ccjm.org/content/74/8/557.abstract AB As research continues to define the optimal management of chronic hepatitis B virus (HBV) infection, clinicians must deal with a number of yet unresolved issues: Should we treat all patients with HBV infection to prevent liver cancer, even if they have no evidence of active disease? Which is the best treatment strategy? What do we do with patients who develop resistance to our current drugs? Should we treat patients with HBV infection who have already developed cirrhosis?