TY - JOUR T1 - Complicated skin and soft-tissue infections: Diagnostic approach and empiric treatment options JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - S21 LP - S28 VL - 74 IS - 8 suppl 4 AU - Susan J. Rehm AU - Alpesh N. Amin AU - James I. Merlino AU - Mark A. Malangoni Y1 - 2007/08/01 UR - http://www.ccjm.org/content/74/8_suppl_4/S21.abstract N2 - Skin and soft-tissue infections are common and generally are uncomplicated at the time of initial presentation. However, these infections can worsen quickly when there are delays in presentation and treatment. Upon encountering these infections, physicians must respond quickly with an appropriate therapeutic plan and be aware of trends in microbial resistance in order to optimize patient care. ER -