RT Journal Article
SR Electronic
T1 An unusual ultrastructural neutrophil abnormality of unknown function
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 49
OP 54
VO 54
IS 1
A2 William R. Hart
A1 Rafael Valenzuela
A1 James T. McMahon
A1 Frank J. Glassy
A1 Joseph A. Golish
A1 Vincent Caggiano
YR 1987
UL http://www.ccjm.org/content/54/1/49.abstract
AB An unusual ultrastructural abnormality of neutrophils is reported in two patients who had bronchogenic carcinoma and idiopathic hypereosinophilic syndrome, respectively. The abnormal neutrophils contained numerous elongated nuclear and cytoplasmic inclusions measuring up to 3 by 0.1 μm. Although the chemical nature, etiology, and functional significance of these inclusions are unknown, they may represent an acquired and reversible neutrophil disorder. In contrast to earlier reported cases, neither patient had infectious complications when the abnormality was found.