RT Journal Article
SR Electronic
T1 Phenytoin toxicity: A cause of reversible monoplegia
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 438
OP 439
VO 54
IS 5
A1 Abdulhadi, Mohamed H.
A1 Notman, Douglas D.
A1 Cardon, Grant C.
A1 Johnston, Presley M.
YR 1987
UL http://www.ccjm.org/content/54/5/438.abstract
AB Phenytoin sodium (Dilantin), a frequently used anticonvulsant, has many well-recognized side effects. Of these, neurological ones are prominent and, when present, usually consist of ataxia, nystagmus, or dysarthria. Phenytoin toxicity in patients with previous strokes may present as a “re-stroke” syndrome. This paper reports a rare but recognizable complication in a patient in whom reversible monoplegia, a focal neurological deficit, developed during long-term phenytoin therapy for grand mal seizures.