RT Journal Article
SR Electronic
T1 Benign essential blepharospasm treated with botulinum toxin
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 421
OP 426
VO 54
IS 5
A1 Berlin, A. Jan
A1 Cassen, Joyce H.
A1 DeNelsky, Garland
A1 Hanson, Maurice R.
A1 Sweeney, Patrick J.
YR 1987
UL http://www.ccjm.org/content/54/5/421.abstract
AB Blepharospasm in 12 patients was graded according to its severity. Six patients also underwent neurological and psychological examinations. All were treated with periocular botulinum toxin injections, and all noted a reduction in spasm severity one week later. The effect lasted 60 to 90 days. The average improvement range was 2 gradations of spasm severity. Complications included a transient ptosis (two patients) and superficial punctate keratopathy (one patient). A psychological component—apparent secondary gain from the blepharospasm—was noted in three patients.