PT - JOURNAL ARTICLE AU - Mayes, James T. AU - Dennis, Vincent W. AU - Hoogwerf, Byron J. TI - Pancreas transplantation in type 1 diabetes: Hope vs reality DP - 2000 Apr 01 TA - Cleveland Clinic Journal of Medicine PG - 281--286 VI - 67 IP - 4 4099 - http://www.ccjm.org/content/67/4/281.short 4100 - http://www.ccjm.org/content/67/4/281.full SO - Cleve Clin J Med2000 Apr 01; 67 AB - Pancreas transplantation can improve quality of life for patients with type 1 diabetes by eliminating hypoglycemic and hyperglycemic episodes, the need for insulin injections, frequent self-monitoring of blood glucose levels, and dietary restrictions. Increasing evidence suggests that it may slow the progression of long-term diabetic complications. On the other hand, patients risk the adverse effects of lifelong immunosuppression.