RT Journal Article SR Electronic T1 Pancreas transplantation in type 1 diabetes: Hope vs reality JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 281 OP 286 VO 67 IS 4 A1 Mayes, James T. A1 Dennis, Vincent W. A1 Hoogwerf, Byron J. YR 2000 UL http://www.ccjm.org/content/67/4/281.abstract AB Pancreas transplantation can improve quality of life for patients with type 1 diabetes by eliminating hypoglycemic and hyperglycemic episodes, the need for insulin injections, frequent self-monitoring of blood glucose levels, and dietary restrictions. Increasing evidence suggests that it may slow the progression of long-term diabetic complications. On the other hand, patients risk the adverse effects of lifelong immunosuppression.