PT - JOURNAL ARTICLE AU - Pien, Lily C. TI - Appropriate use of second-generation antihistamines DP - 2000 May 01 TA - Cleveland Clinic Journal of Medicine PG - 372--380 VI - 67 IP - 5 4099 - http://www.ccjm.org/content/67/5/372.short 4100 - http://www.ccjm.org/content/67/5/372.full SO - Cleve Clin J Med2000 May 01; 67 AB - Antihistamines, one of the most frequently used groups of medications in the United States, are primarily used in treating allergic rhinitis and urticaria and also anaphylactic reactions, pruritus, and symptoms of anxiety. Second-generation antihistamines are safe and effective for treating allergic conditions. Control of nasal congestion may require additional medication. Further studies will determine if second-generation antihistamines can be used for other medical conditions.