PT - JOURNAL ARTICLE AU - Geers, Teresa A. AU - Isada, Carlos M. TI - Update on antiviral therapy for genital herpes infection DP - 2000 Aug 01 TA - Cleveland Clinic Journal of Medicine PG - 567--573 VI - 67 IP - 8 4099 - http://www.ccjm.org/content/67/8/567.short 4100 - http://www.ccjm.org/content/67/8/567.full SO - Cleve Clin J Med2000 Aug 01; 67 AB - For the primary infection of genital herpes, antiviral therapy with acyclovir is the gold standard. For recurrences, there are two options: antiviral treatment of each outbreak as it arises, or suppression of outbreaks with daily oral therapy. Patients tend to prefer the latter because it can decrease the number and severity of outbreaks, but it increases asymptomatic viral shedding and, therefore, the risk of unwittingly transmitting herpes simplex virus to uninfected sexual partners.