PT - JOURNAL ARTICLE AU - Adams, Sandra G. AU - Anzueto, Antonio TI - Treating acute exacerbations of chronic bronchitis in the face of antibiotic resistance DP - 2000 Sep 01 TA - Cleveland Clinic Journal of Medicine PG - 625--633 VI - 67 IP - 9 4099 - http://www.ccjm.org/content/67/9/625.short 4100 - http://www.ccjm.org/content/67/9/625.full SO - Cleve Clin J Med2000 Sep 01; 67 AB - Antibiotics can be effective against acute exacerbations of chronic bronchitis and chronic obstructive pulmonary disease, but with bacterial resistance to multiple antibiotics increasing worldwide, appropriate antibiotic selection is critical. Categorizing patients with acute exacerbations according to age, number of exacerbations per year, disease severity, degree of pulmonary impairment, and presence of comorbid conditions helps to direct therapy.