RT Journal Article SR Electronic T1 The evolving role of hormone therapy in advanced prostate cancer JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 720 OP 726 VO 67 IS 10 A2 Markman, Maurie A1 Dreicer, Robert YR 2000 UL http://www.ccjm.org/content/67/10/720.abstract AB Earlier diagnosis and treatment of prostate cancer has changed the face of late-stage disease, and the use of mainstay hormonal therapies—orchiectomy, luteinizing hormone releasing-hormone analogs, and combined androgen ablation—are evolving rapidly. New approaches such as antiandrogen monotherapy and intermittent therapy are being evaluated. In addition, palliative treatments for patients with androgen-independent tumors have expanded.