RT Journal Article SR Electronic T1 Primary pulmonary hypertension: Update on pathogenesis and novel therapies JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 175 OP 190 VO 67 IS 3 A1 Arroliga, Alejandro C. A1 Dweik, Raed A. A1 Kaneko, F. J. Takao A1 Erzurum, Serpil C. YR 2000 UL http://www.ccjm.org/content/67/3/175.abstract AB Primary pulmonary hypertension is a progressive and fatal disease that chiefly affects young adults. Although its etiology is a mystery, recent research has uncovered several biochemical derangements in this disorder, and new therapies are prolonging survival.