RT Journal Article
SR Electronic
T1 Results of transsphenoidal surgery for Cushing’s disease
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 357
OP 364
VO 55
IS 4
A1 Janet W. Bay
A1 Leslie R. Sheeler
YR 1988
UL http://www.ccjm.org/content/55/4/357.abstract
AB Thirty-six patients with Cushing’s disease underwent transsphenoidal surgery at the Cleveland Clinic between January 1976 and August 1986. Adenomas were identified, removed, and verified pathologically in 28 patients (78%); in all cases, hypercortisolism was corrected. Overall, 31 of the 36 patients (8 6 %) were cured initially (biochemically and clinically). No operative mortality or permanent neurological sequelae were sustained. Follow-up ranged from four to 120 months. There have been three recurrences after an initial apparent cure.