RT Journal Article
SR Electronic
T1 The fibrinolytic system
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 531
OP 541
VO 55
IS 6
A2 Hart, William R.
A1 Lucas, Fred V.
A1 Miller, Michael L.
YR 1988
UL http://www.ccjm.org/content/55/6/531.abstract
AB The fibrinolytic system is the subject of renewed and intense interest. As understanding of its complexity at the biochemical level has increased, appreciation of the role of this system in the pathophysiology of cardiovascular disease has grown. In addition, techniques in molecular biology have been applied to various proteins in the system to produce larger quantities of traditional and genetically engineered plasminogen activators. Many of these advances at a biochemical and molecular level will be increasingly translated into clinical medical practice and practical clinical laboratory tests. This review highlights some of these advances and the laboratory tests that may be employed.