RT Journal Article SR Electronic T1 Postoperative nausea and vomiting JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 549 OP 552 VO 55 IS 6 A1 Bloomfield, Eric A1 Hilberman, Mark A1 Brown, Phillip A1 Noe, Hilda A1 Gaydos, John A1 Miller, Gail A1 Sherrill, Duane A1 Williams, George YR 1988 UL http://www.ccjm.org/content/55/6/549.abstract AB Postoperative nausea and vomiting have been associated with the use of nitrous oxide and, in some studies, with isoflurane. Sufentanil, a new synthetic narcotic with a duration as long as fentanyl, was studied with regard to postoperative nausea and vomiting. A total of 63 patients undergoing extra-abdominal procedures (excluding thoracotomies and intracranial, ophthalmologic, and middle-ear surgery) was studied and randomly divided into four groups: Group A, sufentanil/N2O/O2 with 0.25% isoflurane; Group B, O2/N2O/isoflurane; Group C, O2/isoflurane/sufentanil; Group D, O2/isoflurane. Patients with a history of postoperative nausea and vomiting were excluded. The incidence of postoperative nausea and vomiting was observed in the recovery room. The overall incidence of nausea was 25% and of vomiting 9.5%; differences between techniques were not statistically significant.