PT  - JOURNAL ARTICLE
AU  - Ellis, Keith
AU  - Brener, Sorin
TI  - New fibrinolytic agents for MI: As effective as current agents, but easier to administer
DP  - 2004 Jan 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 20--37
VI  - 71
IP  - 1
4099  - http://www.ccjm.org/content/71/1/20.short
4100  - http://www.ccjm.org/content/71/1/20.full
SO  - Cleve Clin J Med2004 Jan 01; 71
AB  - The efficacy and safety of fibrinolytic agents have not dramatically changed since alteplase (Activase), a derivative of tissue plasminogen activator (t-PA), was introduced nearly 2 decades ago. However, newer agents have a longer half-life, making them easier to deliver. Fibrinolytic therapy is underused in many patients, especially in those traditionally thought to be at high risk for complications.