RT Journal Article
SR Electronic
T1 New fibrinolytic agents for MI: As effective as current agents, but easier to administer
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 20
OP 37
VO 71
IS 1
A1 Ellis, Keith
A1 Brener, Sorin
YR 2004
UL http://www.ccjm.org/content/71/1/20.abstract
AB The efficacy and safety of fibrinolytic agents have not dramatically changed since alteplase (Activase), a derivative of tissue plasminogen activator (t-PA), was introduced nearly 2 decades ago. However, newer agents have a longer half-life, making them easier to deliver. Fibrinolytic therapy is underused in many patients, especially in those traditionally thought to be at high risk for complications.