RT Journal Article
SR Electronic
T1 Recent trials of antioxidant therapy: What should we be telling our patients?
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 327
OP 334
VO 71
IS 4
A1 Hasnain, Bibi I.
A1 Mooradian, Arshag D.
YR 2004
UL http://www.ccjm.org/content/71/4/327.abstract
AB The current evidence does not support the indiscriminate use of vitamins A, C, or E or beta carotene to prevent or reduce cardiovascular disease. Despite a plausible theory that antioxidants can prevent diseases caused by oxidative damage, trials thus far have not proven this. In fact, some studies found antioxidants may be harmful in some people. We review important studies of the effects of four antioxidants (vitamins A, C, and E, and beta carotene) and analyze whether the current evidence supports or confirms or rejects the presumed protective role.