@article {Palumbo385, author = {Pasquale J. Palumbo}, title = {The case for insulin treatment early in type 2 diabetes}, volume = {71}, number = {5}, pages = {385--405}, year = {2004}, publisher = {Cleveland Clinic Journal of Medicine}, abstract = {Most patients with type 2 diabetes ultimately need insulin therapy. This paper presents the case for starting insulin therapy sooner rather than later, preferably without oral drugs and in a {\textquotedblleft}basal/bolus{\textquotedblright} regimen consisting of a daily dose of a long-acting insulin for basal coverage plus preprandial doses of a short-acting insulin.}, issn = {0891-1150}, URL = {https://www.ccjm.org/content/71/5/385}, eprint = {https://www.ccjm.org/content/71/5/385.full.pdf}, journal = {Cleveland Clinic Journal of Medicine} }