RT Journal Article SR Electronic T1 The case for insulin treatment early in type 2 diabetes JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 385 OP 405 VO 71 IS 5 A1 Pasquale J. Palumbo YR 2004 UL http://www.ccjm.org/content/71/5/385.abstract AB Most patients with type 2 diabetes ultimately need insulin therapy. This paper presents the case for starting insulin therapy sooner rather than later, preferably without oral drugs and in a “basal/bolus” regimen consisting of a daily dose of a long-acting insulin for basal coverage plus preprandial doses of a short-acting insulin.