PT  - JOURNAL ARTICLE
AU  - Khush, Kiran K.
AU  - Waters, David
TI  - Lessons from the PROVE-IT Trial
DP  - 2004 Aug 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 609--616
VI  - 71
IP  - 8
4099  - http://www.ccjm.org/content/71/8/609.short
4100  - http://www.ccjm.org/content/71/8/609.full
SO  - Cleve Clin J Med2004 Aug 01; 71
AB  - The Pravastatin or Atorvastatin Evaluation and Infection Therapy trial (PROVE-IT/TIMI-22) showed that in patients with acute coronary syndromes, aggressive lipid-lowering using atorvastatin 80 mg/day provided greater protection against death or major cardiovascular events than did moderate lipid-lowering using pravastatin 40 mg/day. Lowering the low-density lipoprotein cholesterol level to approximately 62 mg/dL with atorvastatin resulted in a 16% reduction in cardiovascular end points.