PT - JOURNAL ARTICLE AU - Majhail, Navneet S. AU - Lichtin, Alan E. TI - Acute leukemia with a very high leukocyte count: Confronting a medical emergency DP - 2004 Aug 01 TA - Cleveland Clinic Journal of Medicine PG - 633--637 VI - 71 IP - 8 4099 - http://www.ccjm.org/content/71/8/633.short 4100 - http://www.ccjm.org/content/71/8/633.full SO - Cleve Clin J Med2004 Aug 01; 71 AB - From 5% to 30% of adult patients with acute leukemias present with hyperleukocytosis—very high white blood cell counts (> 100,000 cells/mm3)—and symptoms of leukostasis. These conditions are a medical emergency that needs prompt recognition and initiation of therapy to prevent respiratory failure or intracranial hemorrhage. Patients should be referred as soon as possible for induction chemotherapy and leukapheresis.