RT Journal Article
SR Electronic
T1 Acute leukemia with a very high leukocyte count: Confronting a medical emergency
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 633
OP 637
VO 71
IS 8
A1 Majhail, Navneet S.
A1 Lichtin, Alan E.
YR 2004
UL http://www.ccjm.org/content/71/8/633.abstract
AB From 5% to 30% of adult patients with acute leukemias present with hyperleukocytosis—very high white blood cell counts (> 100,000 cells/mm3)—and symptoms of leukostasis. These conditions are a medical emergency that needs prompt recognition and initiation of therapy to prevent respiratory failure or intracranial hemorrhage. Patients should be referred as soon as possible for induction chemotherapy and leukapheresis.