PT  - JOURNAL ARTICLE
AU  - Lentz, Steven R.
AU  - Haynes, William G.
TI  - Homocysteine: Is it a clinically important cardiovascular risk factor?
DP  - 2004 Sep 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 729--734
VI  - 71
IP  - 9
4099  - http://www.ccjm.org/content/71/9/729.short
4100  - http://www.ccjm.org/content/71/9/729.full
SO  - Cleve Clin J Med2004 Sep 01; 71
AB  - Elevated plasma homocysteine is associated with an increased risk of myocardial infarction, stroke, and venous thromboembolism. Folic acid and other B vitamins lower plasma homocysteine levels, but whether this therapy confers a clinical benefit has yet to be determined. Until we know the results of ongoing clinical trials of homocysteine-lowering therapy, testing for and treating elevated homocysteine is probably justified only in patients with known cardiovascular disease or who are at high risk.