RT Journal Article
SR Electronic
T1 Homocysteine: Is it a clinically important cardiovascular risk factor?
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 729
OP 734
VO 71
IS 9
A1 Lentz, Steven R.
A1 Haynes, William G.
YR 2004
UL http://www.ccjm.org/content/71/9/729.abstract
AB Elevated plasma homocysteine is associated with an increased risk of myocardial infarction, stroke, and venous thromboembolism. Folic acid and other B vitamins lower plasma homocysteine levels, but whether this therapy confers a clinical benefit has yet to be determined. Until we know the results of ongoing clinical trials of homocysteine-lowering therapy, testing for and treating elevated homocysteine is probably justified only in patients with known cardiovascular disease or who are at high risk.