TY - JOUR T1 - Cholesterol guidelines update: More aggressive therapy for higher-risk patients JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 253 LP - 262 VL - 72 IS - 3 AU - Julie C. Huang AU - Byron J. Hoogwerf Y1 - 2005/03/01 UR - http://www.ccjm.org/content/72/3/253.abstract N2 - The 2004 update to the National Cholesterol Education Program guidelines goes farther than the 2001 version in suggesting an optional low-density lipopro-tein cholesterol (LDL-C) goal of less than 70 mg/dL for patients at “very high risk.” It recommends starting both diet and drug therapy in all patients at high or very high risk whose LDL-C level is above the goal level, with the goal of reducing LDL-C by 30% to 40%. These more aggressive guidelines are based on results of five clinical studies published since 2001. ER -