PT - JOURNAL ARTICLE AU - Jaffer, Amir K. AU - Brotman, Daniel J. AU - Michota, Franklin TI - Current and emerging options in the management of venous thromboembolism DP - 2005 Apr 01 TA - Cleveland Clinic Journal of Medicine PG - S14--S23 VI - 72 IP - 4 suppl 1 4099 - http://www.ccjm.org/content/72/4_suppl_1/S14.short 4100 - http://www.ccjm.org/content/72/4_suppl_1/S14.full SO - Cleve Clin J Med2005 Apr 01; 72 AB - Venous thromboembolism (VTE) is a common disease whose diagnosis is challenging. The best diagnostic approaches combine the patient’s pretest clinical probability of disease with D-dimer testing and/or diagnostic imaging. In light of several advantages, low-molecular-weight heparins are now recommended over unfractionated heparin for most patients with acute VTE. Newer anticoagulants such as the factor Xa inhibitor fondaparinux also show promise for acute VTE. For chronic management, the duration and intensity of warfarin therapy should be tailored to the individual patient.