PT - JOURNAL ARTICLE AU - Tesar, George E. TI - Treating depression in a mother of five: What to do when the first step fails DP - 2005 Jun 01 TA - Cleveland Clinic Journal of Medicine PG - 501--506 VI - 72 IP - 6 4099 - http://www.ccjm.org/content/72/6/501.short 4100 - http://www.ccjm.org/content/72/6/501.full SO - Cleve Clin J Med2005 Jun 01; 72 AB - What should one do with a depressed patient who does not get better? If depression does not respond to an antidepressant given in adequate doses for an adequate time, logical next steps include increasing the dose, adding a different medication, or adding a nonpharmacologic therapy. Or one can reconsider the diagnosis.