PT  - JOURNAL ARTICLE
AU  - Olech, Ewa
AU  - Merrill, Joan T.
TI  - DHEA supplementation: The claims in perspective
DP  - 2005 Nov 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 965--984
VI  - 72
IP  - 11
4099  - http://www.ccjm.org/content/72/11/965.short
4100  - http://www.ccjm.org/content/72/11/965.full
SO  - Cleve Clin J Med2005 Nov 01; 72
AB  - Deficiency of dehydroepiandrosterone (DHEA) is associated with lupus erythematosus, diabetes mellitus, Alzheimer disease, and some cancers, but we are not yet ready to conclude that prescribing supplemental DHEA is helpful in these or any other conditions. DHEA shows some promise in observational clinical studies and laboratory experiments, but we still need large-scale human studies to answer key questions. For now, we do not have enough evidence to recommend routine treatment with DHEA. As with other supplements, quality control is always a concern, and different brands may contain different amounts of active ingredient.