RT Journal Article
SR Electronic
T1 DHEA supplementation: The claims in perspective
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 965
OP 984
VO 72
IS 11
A1 Olech, Ewa
A1 Merrill, Joan T.
YR 2005
UL http://www.ccjm.org/content/72/11/965.abstract
AB Deficiency of dehydroepiandrosterone (DHEA) is associated with lupus erythematosus, diabetes mellitus, Alzheimer disease, and some cancers, but we are not yet ready to conclude that prescribing supplemental DHEA is helpful in these or any other conditions. DHEA shows some promise in observational clinical studies and laboratory experiments, but we still need large-scale human studies to answer key questions. For now, we do not have enough evidence to recommend routine treatment with DHEA. As with other supplements, quality control is always a concern, and different brands may contain different amounts of active ingredient.