PT - JOURNAL ARTICLE AU - Julia Bucklan AU - Zubair Ahmed TI - CGRP antagonists for decreasing migraine frequency: New options, long overdue AID - 10.3949/ccjm.87a.19048 DP - 2020 Apr 01 TA - Cleveland Clinic Journal of Medicine PG - 211--218 VI - 87 IP - 4 4099 - http://www.ccjm.org/content/87/4/211.short 4100 - http://www.ccjm.org/content/87/4/211.full SO - Cleve Clin J Med2020 Apr 01; 87 AB - The cornerstone of preventive migraine treatment has long been drugs developed for other diseases such as epilepsy, depression, and hypertension. But a new set of drugs is available for preventing migraine attacks: erenumab, galcanezumab, fremanezumab, and eptinezumab. These monoclonal antibodies target calcitonin gene-related peptide (CGRP) or its receptors, each a key molecule in the pathophysiology of migraine.